Bluegrass Biodesign — Cardiology / Cardiothoracic Surgery Team

University of Louisville · 2025–2026 Cohort

Medical Device Cardiology / CT Surgery UofL School of Medicine J.B. Speed School of Engineering NSF I-Corps
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What is Bluegrass Biodesign

Bluegrass Biodesign is a nine-month interdisciplinary innovation program at the University of Louisville that trains the next generation of medical device developers. Students from the School of Medicine, College of Business, and J.B. Speed School of Engineering work in multidisciplinary teams to identify unmet clinical needs, design solutions, prototype devices, and validate them against real-world constraints.

The program is grounded in the Stanford Biodesign framework — a structured methodology moving from clinical need-finding through prototyping and market validation. All teams complete business training through UofL's NSF-funded I-Corps program, receiving funding and mentorship to bring their ideas to life.

Our Device

Our team worked in the Cardiology and Cardiothoracic Surgery space, identifying an unmet clinical need through direct observation and physician interviews with our mentors Dr. Shahab Ghafghazi, MD and Dr. Guruprasad Giridharan, PhD. Working alongside medical students Amos Flomo, Ellen Oskoui, Caleb He, and Nikita Nair, and our engineering teammates, we designed, prototyped, and tested a device aimed at improving outcomes in the CT surgery setting.

Prototyping involved everything from late-night study sessions with circuit boards to using each other as test subjects — all in the spirit of actually making something that works.

Gallery

Cardiology/CT Surgery Team — Deliverable 1 presentation
The team after our first deliverable presentation — October 2025
Device prototyping and testing session
Early prototype testing session
Testing the device on a teammate
Using teammates as test subjects
Device prototype with sensors
Late night prototyping
Certificate of Completion — Bluegrass Biodesign Program
Certificates of Completion — February 2026

The Biodesign Process

01
Need-Finding
Clinical observations and physician interviews to identify real unmet needs
02
Need Statement
Define the problem with precision before proposing any solution
03
Ideation
Generate and screen hundreds of concepts against clinical and technical criteria
04
Prototyping
Rapid physical builds and iterative testing in collaboration with engineers
05
Validation
Market discovery and user testing through UofL's NSF I-Corps program
06
Pitch
Present the solution, business case, and regulatory pathway to stakeholders
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